Blog Author: Archita Khaire
Diabetes is one of today’s greatest global problems. As per International Diabetes Federation, currently there are more than 450 million people suffering from diabetes across the globe and count is projected to increase to 700 million by 2045. It is one of the fastest growing emergency causing 4 million deaths worldwide every year.
Image Credit: International Diabetes Federation
You may not feel any symptoms from diabetes at first. High blood sugar (hyperglycemia) and high levels of insulin (the hormone that manages blood sugar levels) start to damage your body silently, many years before you’re diagnosed with diabetes.
Glucose is the fuel that feeds your body’s cells, but to enter your cells it needs a key. Insulin is that key. People with type 1 diabetes (#T1D) don’t produce insulin. People with type 2 diabetes (#T2D) don’t respond to insulin as well as they should and later in the disease often don’t make enough insulin. The main causes of T2D include lifestyle, physical activity, dietary habits and heredity, whereas T1D is thought to be due to autoimmunological destruction of the Langerhans islets hosting pancreatic-β cells.
Numerous algorithms and different approaches have been applied, such as traditional machine learning algorithms, ensemble learning approaches and association rule learning in order to predict diabetes. Here are few examples:
SVM for diabetes prediction
ANT_FDCSM for diabetes detection
Image Credit: Critical-depth Raman spectroscopy enables home-use non-invasive glucose monitoring (plos.org)
With advances in smart wearables and edge computing, researchers are now building non-invasive devices for continuous glucose monitoring (#CGM). Scientists at MIT have shown that they can use Raman spectroscopy to directly measure glucose concentrations through the skin.
Type 2 diabetes is a complex and progressive disease characterized by various metabolic defects and affecting multiple organs.
Image Credit: https://doi.org/10.1016/j.amjmed.2013.06.007
Chronic diabetic complications include: heart failure, diabetic neuropathy, nephropathy, retinopathy, and diabetic foot.
Multiple machine learning algorithms have been developed for automatic detection of diabetic neuropathy.
Diabetic nephropathy (DN) is defined by elevated urine albumin excretion or reduced glomerular filtration rate (GFR), or both. This serious complication causes destructive scarring in diabetic patients.
Pathologists usually classify DN based on a visual assessment of glomerular pathology using immunofluorescence microscopy and electron microscopy. AI scientists are using image classification algorithms to enhance and fast track the detection of Diabetic nephropathy.
Image Credit: Appl. Sci. 2020, 10(18), 6185; https://doi.org/10.3390/app10186185
For retinopathy as well, researchers have developed image classification algorithms that can detect diabetes from retinal images.
Researchers are experimenting the effectiveness of e-nose technology, using machine learning classifiers, to predict single- and poly-microbial species targeted for diabetic foot infection.
Diabetes Medication and Care
FDA has approved artificial pancreas that automatically monitors blood glucose and provides appropriate insulin doses.
Image Credit: Artificial pancreas system upgraded with AI algorithm (medicalxpress.com)
AI methods have found their way into daily self-management of diabetes, mainly in the form of smartphone apps and wearables such as smart watches: For example, food recognition apps use machine learning methods and cloud-based image analyzing and may help people with diabetes to make more informed food choices and insulin treatment decisions.
Artificial Intelligence is already transforming diabetes care. It will continue to have transformational impact on the everyday lives of people with diabetes.